Dichloromethane → 4-(2-Amino-3-tert-butoxy-butyryl)-3-(6-fluoro-1H-indol-3-yl)-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH:12]2[CH:13]([CH:14]([c:16]3[cH:17][nH:18][c:19]4[cH:20][c:21]([F:25])[cH:22][cH:23][c:24]34)[CH2:15]1)[N:26]([C:29]([CH:30]([CH:31]([CH3:32])[O:33][C:34]([CH3:35])([CH3:36])[CH3:37])[NH:38][C:39]([O:40][C:41]([CH3:42])([CH3:43])[CH3:44])=[O:45])=[O:46])[CH2:27][CH2:28]2.[Cl:54][CH2:55][Cl:56].[F:47][C:48]([F:49])([F:50])[C:51]([OH:52])=[O:53]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH:12]2[CH:13]([CH:14]([c:16]3[cH:17][nH:18][c:19]4[cH:20][c:21]([F:25])[cH:22][cH:23][c:24]34)[CH2:15]1)[N:26]([C:29]([CH:30]([CH:31]([CH3:32])[O:33][C:34]([CH3:35])([CH3:36])[CH3:37])[NH2:38])=[O:46])[CH2:27][CH2:28]2Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-5ede9695e64e4be1aa4f2753dbbde7cb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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