Dichloromethane → 1-Benzyl-N-(3,4-difluorobenzyl)-6-(4,5-dihydrothiazol-2-ylamino)-5-fluoro-2-isopropyl-1H-indole-3-carboxamide
Reaction equation
[CH3:40][CH2:41][N:42]([CH2:43][CH3:44])[CH2:45][CH3:46].[Cl:34][CH2:35][CH2:36][N:37]=[C:38]=[S:39].[Cl:47][CH2:48][Cl:49].[NH2:1][c:2]1[c:3]([F:33])[cH:4][c:5]2[c:6]([C:21](=[O:22])[NH:23][CH2:24][c:25]3[cH:26][c:27]([F:32])[c:28]([F:31])[cH:29][cH:30]3)[c:7]([CH:18]([CH3:19])[CH3:20])[n:8]([CH2:11][c:12]3[cH:13][cH:14][cH:15][cH:16][cH:17]3)[c:9]2[cH:10]1>>[NH:1]([c:2]1[c:3]([F:33])[cH:4][c:5]2[c:6]([C:21](=[O:22])[NH:23][CH2:24][c:25]3[cH:26][c:27]([F:32])[c:28]([F:31])[cH:29][cH:30]3)[c:7]([CH:18]([CH3:19])[CH3:20])[n:8]([CH2:11][c:12]3[cH:13][cH:14][cH:15][cH:16][cH:17]3)[c:9]2[cH:10]1)[C:38]1=[N:37][CH2:36][CH2:35][S:39]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-421652bdd83149a7a169da70c893675f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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