Dichloromethane → 1-Piperidin-4-ylimidazolidine-2,4-dione

HRID 1560292Notes

Reaction equation

HRID 1560292 reaction equation
[Cl:28][CH2:29][Cl:30].[O:8]=[C:9]1[N:10]([CH:15]2[CH2:16][CH2:17][N:18]([C:21]([O:22][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:27])[CH2:19][CH2:20]2)[CH2:11][C:12](=[O:14])[NH:13]1.[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[O:8]=[C:9]1[N:10]([CH:15]2[CH2:16][CH2:17][NH:18][CH2:19][CH2:20]2)[CH2:11][C:12](=[O:14])[NH:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 57428924Tert-butyl 4-(2,4-dioxoimidazolidin-1-yl)piperidine-1-carboxylate

Product 1

HCID 574289231-Piperidin-4-ylimidazolidine-2,4-dione

Sources & evidence

ORD record
ord-24846ecf49d04c06a05a141fc8bc8791
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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