Potassium Cation → 5-(4-Fluorophenyl)-3-thiophenecarboxylic acid ethyl ester

HRID 1560335Notes

Reaction equation

HRID 1560335 reaction equation
[C:22](=[O:23])([O-:24])[O-:25].[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][s:8][c:9]([Br:11])[cH:10]1.[CH3:28][O:29][CH2:30][CH2:31][O:32][CH3:33].[CH3:35][CH2:36][O:37][C:38](=[O:39])[CH3:40].[K+:26].[K+:27].[OH2:34].[OH:12][B:13]([OH:14])[c:15]1[cH:16][cH:17][c:18]([F:19])[cH:20][cH:21]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][s:8][c:9](-[c:15]2[cH:16][cH:17][c:18]([F:19])[cH:20][cH:21]2)[cH:10]1

Participants

8

Reactant 7

HCID 813Potassium Cation2×HCID 962WaterHCID 80711,2-DimethoxyethaneHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 2856454-Fluorophenylboronic acidHCID 15293216Ethyl 5-bromothiophene-3-carboxylate

Product 1

HCID 587391355-(4-Fluorophenyl)-3-thiophenecarboxylic acid ethyl ester

Sources & evidence

ORD record
ord-eef78c7e63d54536b2fda705f3c92bed
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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