Methanol → 4-(7-Chloro-quinazolin-4-yl)-piperidine-1-carboxylic acid (4-isopropoxy-phenyl)-amide
Reaction equation
[CH3:50][OH:51].[CH:18]([N:19]([CH2:20][CH3:21])[CH:22]([CH3:23])[CH3:24])([CH3:25])[CH3:26].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([CH:12]3[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]3)[n:7][cH:8][n:9][c:10]2[cH:11]1.[N+:27]([c:28]1[cH:29][cH:30][c:31]([O:36][C:37](=[O:32])[NH:38][c:39]2[cH:40][cH:41][c:42]([O:45][CH:46]([CH3:47])[CH3:48])[cH:43][cH:44]2)[cH:33][cH:34]1)([O-:35])=[O:49]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([CH:12]3[CH2:13][CH2:14][N:15]([C:37](=[O:36])[NH:38][c:39]4[cH:40][cH:41][c:42]([O:45][CH:46]([CH3:47])[CH3:48])[cH:43][cH:44]4)[CH2:16][CH2:17]3)[n:7][cH:8][n:9][c:10]2[cH:11]1Participants
5
Sources & evidence
- ORD record
- ord-f5253ed3d1cb47cbb5a13fee5f49b9f4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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