Dichloromethane → 3-[(4-Chloro-2,6-difluorophenyl)(cyclopropyl)methyl]-7-[(methylsulfanyl)methyl]-1H-indole
Reaction equation
[CH3:22][S:23][CH2:24][c:25]1[cH:26][cH:27][cH:28][c:29]2[cH:30][cH:31][nH:32][c:33]12.[Cl:1][c:2]1[cH:3][c:4]([F:14])[c:5]([CH:9]([OH:10])[CH:11]2[CH2:12][CH2:13]2)[c:6]([F:8])[cH:7]1.[Cl:34][CH2:35][Cl:36].[OH:15][C:16]([C:17]([F:18])([F:19])[F:20])=[O:21]>>[Cl:1][c:2]1[cH:3][c:4]([F:14])[c:5]([CH:9]([CH:11]2[CH2:12][CH2:13]2)[c:30]2[c:29]3[cH:28][cH:27][cH:26][c:25]([CH2:24][S:23][CH3:22])[c:33]3[nH:32][cH:31]2)[c:6]([F:8])[cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-dcb213030e114705ace8c9a5893c23b5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…