Dichloromethane → Prop-2-enyl 4-[[7-(2-fluoro-4-methylsulfonylphenyl)-5,6-dihydropyrrolo[2,3-d]pyrimidin-4-yl]oxy]piperidine-1-carboxylate

HRID 1561142Notes

Reaction equation

HRID 1561142 reaction equation
[CH3:32][CH2:33][N:34]([CH2:35][CH3:36])[CH2:37][CH3:38].[Cl:39][CH2:40][Cl:41].[F:1][c:2]1[c:3]([N:12]2[CH2:13][CH2:14][c:15]3[c:16]2[n:17][cH:18][n:19][c:20]3[O:21][CH:22]2[CH2:23][CH2:24][N:25]([C:28](=[O:29])[O:30][CH3:31])[CH2:26][CH2:27]2)[cH:4][cH:5][c:6]([S:8](=[O:9])(=[O:10])[CH3:11])[cH:7]1>>[F:1][c:2]1[c:3]([N:12]2[CH2:13][CH2:14][c:15]3[c:16]2[n:17][cH:18][n:19][c:20]3[O:21][CH:22]2[CH2:23][CH2:24][N:25]([C:28](=[O:29])[O:30][CH2:31][CH:32]=[CH2:33])[CH2:26][CH2:27]2)[cH:4][cH:5][c:6]([S:8](=[O:9])(=[O:10])[CH3:11])[cH:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 24897458Methyl 4-[[7-(2-fluoro-4-methylsulfonylphenyl)-5,6-dihydropyrrolo[2,3-d]pyrimidin-4-yl]oxy]piperidine-1-carboxylate

Product 1

HCID 58017044Prop-2-enyl 4-[[7-(2-fluoro-4-methylsulfonylphenyl)-5,6-dihydropyrrolo[2,3-d]pyrimidin-4-yl]oxy]piperidine-1-carboxylate

Sources & evidence

ORD record
ord-9996c2f3ed4c452fab0b905927a8fb77
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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