Dichloromethane → HCID 178469835, compound

HRID 1561150Notes

Reaction equation

[CH2:56]([CH3:57])[O:58][C:59](=[O:60])[c:61]1[n:62][cH:63][c:64]([NH2:67])[n:65][cH:66]1.[CH:32]([N:33]([CH2:34][CH3:35])[CH:36]([CH3:37])[CH3:38])([CH3:39])[CH3:40].[Cl:1][c:2]1[c:3]([F:31])[c:4]([CH:8]2[CH:9]([C:28](=[O:29])[OH:30])[NH:10][CH:11]([CH2:23][C:24]([CH3:25])([CH3:26])[CH3:27])[C:12]2([C:13]#[N:14])[c:15]2[c:16]([F:22])[cH:17][c:18]([Cl:21])[cH:19][cH:20]2)[cH:5][cH:6][cH:7]1.[Cl:68][CH2:69][Cl:70].[c:41]1([P:42]([Cl:43])([c:44]2[cH:45][cH:46][cH:47][cH:48][cH:49]2)=[O:50])[cH:51][cH:52][cH:53][cH:54][cH:55]1>>[Cl:1][c:2]1[c:3]([F:31])[c:4]([CH:8]2[CH:9]([C:28](=[O:30])[NH:67][c:64]3[cH:63][n:62][c:61]([C:59]([O:58][CH2:56][CH3:57])=[O:60])[cH:66][n:65]3)[NH:10][CH:11]([CH2:23][C:24]([CH3:25])([CH3:26])[CH3:27])[C:12]2([C:13]#[N:14])[c:15]2[c:16]([F:22])[cH:17][c:18]([Cl:21])[cH:19][cH:20]2)[cH:5][cH:6][cH:7]1

Participants

Reactant 5

HCID 6344Dichloromethane

HCID 73910Diphenylphosphinic chloride

HCID 81531Diisopropylethylamine

HCID 22271413Ethyl 5-Aminopyrazine-2-carboxylate

HCID 666882513-(3-Chloro-2-fluoro-phenyl)-4-(4-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2-dimethyl-propyl)-pyrrolidine-2-carboxylic acid

Product 1

HCID 178469835HCID 178469835, compound

Sources & evidence

ORD record: ord-62e33abef2e743768a2ade9fd1d5cca0
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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