Potassium Cation → 4-[4-(2-Bromo-ethyl)-4-hydroxy-piperidin-1-yl]-2-trifluoromethyl-benzonitrile
Reaction equation
[C:23](=[O:24])([O-:25])[O-:26].[C:48]([Br:49])([Br:50])([Br:51])[Br:52].[Cl:53][CH2:54][Cl:55].[K+:27].[K+:28].[OH:1][C:2]1([CH2:20][CH2:21][OH:22])[CH2:3][CH2:4][N:5]([c:8]2[cH:9][c:10]([C:16]([F:17])([F:18])[F:19])[c:11]([C:12]#[N:13])[cH:14][cH:15]2)[CH2:6][CH2:7]1.[c:29]1([P:30]([c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[cH:43][cH:44][cH:45][cH:46][cH:47]1>>[OH:1][C:2]1([CH2:20][CH2:21][Br:49])[CH2:3][CH2:4][N:5]([c:8]2[cH:9][c:10]([C:16]([F:17])([F:18])[F:19])[c:11]([C:12]#[N:13])[cH:14][cH:15]2)[CH2:6][CH2:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-7af77250cf274a949bfb5b14a9ce2553
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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