Sodium ion → 4-[1-(1,4-dioxaspiro[4.5]dec-8-yl)-1H-pyrazol-4-yl]-7-[2-(trimethylsilyl)ethoxy]methyl-7H-pyrrolo[2,3-d]pyrimidine

HRID 1561305Notes

Reaction equation

HRID 1561305 reaction equation
[CH3:1][S:2]([O:3][CH:6]1[CH2:7][CH2:8][C:9]2([O:10][CH2:11][CH2:12][O:13]2)[CH2:14][CH2:15]1)(=[O:4])=[O:5].[H-:38].[Na+:39].[O:40]=[CH:41][N:42]([CH3:43])[CH3:44].[nH:16]1[n:17][cH:18][c:19](-[c:21]2[c:22]3[c:23]([n:24][cH:25][n:26]2)[n:27]([CH2:30][O:31][CH2:32][CH2:33][Si:34]([CH3:35])([CH3:36])[CH3:37])[cH:28][cH:29]3)[cH:20]1>>[CH:6]1([n:16]2[n:17][cH:18][c:19](-[c:21]3[c:22]4[c:23]([n:24][cH:25][n:26]3)[n:27]([CH2:30][O:31][CH2:32][CH2:33][Si:34]([CH3:35])([CH3:36])[CH3:37])[cH:28][cH:29]4)[cH:20]2)[CH2:7][CH2:8][C:9]2([O:10][CH2:11][CH2:12][O:13]2)[CH2:14][CH2:15]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6228DimethylformamideHCID 166653HydrideHCID 149667411,4-Dioxaspiro(4.5)decan-8-yl methanesulfonateHCID 426313464-(1H-Pyrazol-4-yl)-7-(2-(trimethylsilyl)ethoxy)methyl-7 H-pyrrolo(2,3-d)-pyrimidine

Product 1

HCID 574779744-[1-(1,4-dioxaspiro[4.5]dec-8-yl)-1H-pyrazol-4-yl]-7-[2-(trimethylsilyl)ethoxy]methyl-7H-pyrrolo[2,3-d]pyrimidine

Sources & evidence

ORD record
ord-f80e9abbdd4744058f62a9caa1733633
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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