Dimethylformamide → 5-Bromo-2-chloronicotinic acid

HRID 1561326Notes

Reaction equation

HRID 1561326 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:9](=[O:10])[OH:11])[c:5]([OH:8])[n:6][cH:7]1.[CH3:16][N:17]([CH3:18])[CH:19]=[O:20].[S:12]([Cl:13])([Cl:14])=[O:15]>>[Br:1][c:2]1[cH:3][c:4]([C:9](=[O:10])[OH:11])[c:5]([Cl:14])[n:6][cH:7]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 24386Thionyl ChlorideHCID 178418525HCID 178418525, compound

Product 1

HCID 27633425-Bromo-2-chloronicotinic acid

Sources & evidence

ORD record
ord-d28011e087a749bf94ba0bccac5c5783
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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