Potassium Cation → 5-chloro-1,3-dihydro-1-(3-methyl-4-piperidinyl)-2H-benzimidazol-2-one

HRID 1561855Notes

Reaction equation

HRID 1561855 reaction equation
[CH3:25][CH:26]([OH:27])[CH3:28].[Cl:1][c:2]1[cH:3][c:4]2[c:5]([n:6]([CH:10]3[CH:11]([CH3:20])[CH2:12][N:13]([C:16]([O:17][CH3:18])=[O:19])[CH2:14][CH2:15]3)[c:7](=[O:9])[nH:8]2)[cH:21][cH:22]1.[K+:24].[OH-:23].[OH2:29]>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([n:6]([CH:10]3[CH:11]([CH3:20])[CH2:12][NH:13][CH2:14][CH2:15]3)[c:7](=[O:9])[nH:8]2)[cH:21][cH:22]1

Participants

6

Reactant 5

HCID 813Potassium CationHCID 961HydroxideHCID 962WaterHCID 3776IsopropanolHCID 21500273methyl 4-(5-chloro-1,3-dihydro-2-oxo-2H-benzimidazol-1-yl)-3-methyl-1-piperidinecarboxylate

Product 1

HCID 215002835-chloro-1,3-dihydro-1-(3-methyl-4-piperidinyl)-2H-benzimidazol-2-one

Sources & evidence

ORD record
ord-871155c3dfa24545998f009c9eae9779
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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