Bicarbonate Ion → Racemic [1-(2,2,2-trifluoro-ethyl)-piperidin-3-yl]-carbamic acid tert-butyl ester
Reaction equation
[C:19]([CH3:20])([CH3:21])([CH3:22])[O:23][C:24]([NH:25][CH:26]1[CH2:27][NH:28][CH2:29][CH2:30][CH2:31]1)=[O:32].[CH3:33][CH2:34][O:35][C:36]([CH3:37])=[O:38].[F:1][C:2]([CH2:3][O:4][S:5]([C:6]([F:7])([F:8])[F:9])(=[O:10])=[O:11])([F:12])[F:13].[Na+:18].[O-:14][C:15]([OH:16])=[O:17].[OH2:39]>>[F:1][C:2]([CH2:3][N:28]1[CH2:27][CH:26]([NH:25][C:24]([O:23][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:32])[CH2:31][CH2:30][CH2:29]1)([F:12])[F:13]Participants
7
Sources & evidence
- ORD record
- ord-54239af75a57446fbec36693d52f15a7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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