Water → Tert-butyl 4-[(3-carbamoyl-8-iodo-4,5-dihydro-1H-pyrazolo[4,3-h]quinazolin-1-yl)methyl]piperidine-1-carboxylate
Reaction equation
[Br:18][CH2:19][CH:20]1[CH2:21][CH2:22][N:23]([C:26](=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32])[CH2:24][CH2:25]1.[C:33](=[O:34])([O-:35])[O-:36].[Cs+:37].[Cs+:38].[I:1][c:2]1[n:3][c:4]2[c:9]([cH:10][n:11]1)[CH2:8][CH2:7][c:6]1[c:5]-2[nH:14][n:13][c:12]1[C:15](=[O:16])[NH2:17].[O:40]=[CH:41][N:42]([CH3:43])[CH3:44].[OH2:39]>>[I:1][c:2]1[n:3][c:4]2[c:9]([cH:10][n:11]1)[CH2:8][CH2:7][c:6]1[c:5]-2[n:14]([CH2:19][CH:20]2[CH2:21][CH2:22][N:23]([C:26](=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32])[CH2:24][CH2:25]2)[n:13][c:12]1[C:15](=[O:16])[NH2:17]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-e8b08fd92888489698ecad2da714040c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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