Dimethyl Sulfoxide → 2-[[3-[2-[tert-butyl(dimethyl)silyl]oxyethoxy]phenyl]methyl-methylamino]-5,6,7-trimethoxy-1H-quinazolin-4-one
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH2:7][CH2:8][O:9][c:10]1[cH:11][c:12]([CH2:13][NH:14][CH3:15])[cH:16][cH:17][cH:18]1)([CH3:19])[CH3:20].[CH3:39][CH2:40][N:41]([CH2:42][CH3:43])[CH2:44][CH3:45].[CH3:47][S:48]([CH3:49])=[O:50].[Cl:21][c:22]1[nH:23][c:24]2[cH:25][c:26]([O:37][CH3:38])[c:27]([O:35][CH3:36])[c:28]([O:33][CH3:34])[c:29]2[c:30](=[O:32])[n:31]1.[OH2:46]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH2:7][CH2:8][O:9][c:10]1[cH:11][c:12]([CH2:13][N:14]([CH3:15])[c:22]2[nH:23][c:24]3[cH:25][c:26]([O:37][CH3:38])[c:27]([O:35][CH3:36])[c:28]([O:33][CH3:34])[c:29]3[c:30](=[O:32])[n:31]2)[cH:16][cH:17][cH:18]1)([CH3:19])[CH3:20]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-461d8659583c4aaab4052f4030478f76
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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