Dimethyl Sulfoxide → 1-(4-(4-(2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)butyl)-4-methylpyridin-2(1H)-one
Reaction equation
[C:14]([CH3:15])([CH3:16])([CH3:17])[c:18]1[n:19][c:20]([C:30]([F:31])([F:32])[F:33])[cH:21][c:22]([N:24]2[CH2:25][CH2:26][NH:27][CH2:28][CH2:29]2)[n:23]1.[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40].[CH3:42][S:43](=[O:44])[CH3:45].[Cl:1][CH2:2][CH2:3][CH2:4][CH2:5][n:6]1[c:7](=[O:13])[cH:8][c:9]([CH3:12])[cH:10][cH:11]1.[OH2:41]>>[CH2:2]([CH2:3][CH2:4][CH2:5][n:6]1[c:7](=[O:13])[cH:8][c:9]([CH3:12])[cH:10][cH:11]1)[N:27]1[CH2:26][CH2:25][N:24]([c:22]2[cH:21][c:20]([C:30]([F:31])([F:32])[F:33])[n:19][c:18]([C:14]([CH3:15])([CH3:16])[CH3:17])[n:23]2)[CH2:29][CH2:28]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-457fa00589c24bb494585ec63df68b45
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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