Methanol → 1-tert-Butyl 4-methyl 4-methylpiperidine-1,4-dicarboxylate

HRID 1562195Notes

Reaction equation

HRID 1562195 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([C:14](=[O:15])[OH:16])([CH3:17])[CH2:12][CH2:13]1.[CH3:18][Si:19]([CH:20]=[N+:21]=[N-:22])([CH3:23])[CH3:24].[CH3:25][OH:26].[CH3:27][c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([C:14](=[O:15])[O:16][CH3:18])([CH3:17])[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 887MethanolHCID 1140TolueneHCID 167693TrimethylsilyldiazomethaneHCID 232828481-[(Tert-butoxy)carbonyl]-4-methylpiperidine-4-carboxylic acid

Product 1

HCID 463183881-tert-Butyl 4-methyl 4-methylpiperidine-1,4-dicarboxylate

Sources & evidence

ORD record
ord-50e2d34349ff4245a9013159e39d1e82
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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