Isopropanol → N-[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]-5-fluoroquinazolin-4-amine
Reaction equation
[CH:29]([OH:30])([CH3:31])[CH3:32].[Cl:13][c:14]1[cH:15][c:16]([NH2:17])[cH:18][cH:19][c:20]1[O:21][CH2:22][c:23]1[n:24][cH:25][cH:26][cH:27][cH:28]1.[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]2[cH:7][cH:8][cH:9][c:10]([F:12])[c:11]12>>[c:2]1([NH:17][c:16]2[cH:15][c:14]([Cl:13])[c:20]([O:21][CH2:22][c:23]3[n:24][cH:25][cH:26][cH:27][cH:28]3)[cH:19][cH:18]2)[n:3][cH:4][n:5][c:6]2[cH:7][cH:8][cH:9][c:10]([F:12])[c:11]12Participants
4
Sources & evidence
- ORD record
- ord-84b02a12ecf8495dbdf349b05cc70ef6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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