Methanol → Tert-butyl 4-oxo-3,4-dihydrospiro[1-benzopyran-2,4'-piperidine]-1'-carboxylate

HRID 1562780Notes

Reaction equation

HRID 1562780 reaction equation
[C:11](=[O:12])([O:13][C:14]([CH3:15])([CH3:16])[CH3:17])[N:18]1[CH2:19][CH2:20][C:21](=[O:24])[CH2:22][CH2:23]1.[CH2:27]1[CH2:28][NH:29][CH2:30][CH2:31]1.[CH3:25][OH:26].[OH:1][c:2]1[c:3]([C:8]([CH3:9])=[O:10])[cH:4][cH:5][cH:6][cH:7]1>>[O:1]1[c:2]2[c:3]([cH:4][cH:5][cH:6][cH:7]2)[C:8](=[O:10])[CH2:9][C:21]12[CH2:20][CH2:19][N:18]([C:11](=[O:12])[O:13][C:14]([CH3:15])([CH3:16])[CH3:17])[CH2:23][CH2:22]2

Participants

5

Reactant 4

HCID 887MethanolHCID 83752'-HydroxyacetophenoneHCID 31268PyrrolidineHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

Product 1

HCID 40427565Tert-butyl 4-oxo-3,4-dihydrospiro[1-benzopyran-2,4'-piperidine]-1'-carboxylate

Sources & evidence

ORD record
ord-fc36db144bb849af816ddcd4caa16c39
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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