Dichloromethane → benzyl 4-[(1H-indazol-5-ylamino)sulfonyl]piperidine-1-carboxylate

HRID 156310Notes

Reaction equation

HRID 156310 reaction equation
[CH2:43]([Cl:44])[Cl:45].[O:8]1[CH2:9][CH2:10][CH2:11][CH2:12][CH:13]1[n:14]1[n:15][cH:16][c:17]2[cH:18][c:19]([NH:23][S:24](=[O:25])(=[O:26])[CH:27]3[CH2:28][CH2:29][N:30]([C:33](=[O:34])[O:35][CH2:36][c:37]4[cH:38][cH:39][cH:40][cH:41][cH:42]4)[CH2:31][CH2:32]3)[cH:20][cH:21][c:22]12.[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[nH:14]1[n:15][cH:16][c:17]2[cH:18][c:19]([NH:23][S:24](=[O:25])(=[O:26])[CH:27]3[CH2:28][CH2:29][N:30]([C:33](=[O:34])[O:35][CH2:36][c:37]4[cH:38][cH:39][cH:40][cH:41][cH:42]4)[CH2:31][CH2:32]3)[cH:20][cH:21][c:22]12

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 69431167benzyl 4-{[(1-tetrahydro-2H-pyran-2-yl-1H-indazol-5-yl)amino]sulfonyl}-1-piperidinecarboxylate

Product 1

HCID 18447213benzyl 4-[(1H-indazol-5-ylamino)sulfonyl]piperidine-1-carboxylate

Sources & evidence

ORD record
ord-c64c3243542346e092981199b5e072d0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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