Hydrochloric Acid → 1-{3-[4-(4-fluorobenzoyl)-1-piperidinyl]propyl}-1,3-dihydro-5-(trifluoromethyl)-2H-benzimidazol-2-one
Reaction equation
[CH3:43][CH:44]([CH3:45])[CH2:46][C:47](=[O:48])[CH3:49].[Cl:1][CH2:2][CH2:3][CH2:4][n:5]1[c:6](=[O:18])[nH:7][c:8]2[c:9]1[cH:10][cH:11][c:12]([C:14]([F:15])([F:16])[F:17])[cH:13]2.[ClH:19].[F:20][c:21]1[cH:22][cH:23][c:24]([C:27](=[O:28])[CH:29]2[CH2:30][CH2:31][NH:32][CH2:33][CH2:34]2)[cH:25][cH:26]1.[I-:42].[K+:41].[Na+:35].[Na+:36].[O-:37][C:38](=[O:39])[O-:40]>>[CH2:2]([CH2:3][CH2:4][n:5]1[c:6](=[O:18])[nH:7][c:8]2[c:9]1[cH:10][cH:11][c:12]([C:14]([F:15])([F:16])[F:17])[cH:13]2)[N:32]1[CH2:31][CH2:30][CH:29]([C:27]([c:24]2[cH:23][cH:22][c:21]([F:20])[cH:26][cH:25]2)=[O:28])[CH2:34][CH2:33]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-f26b6b4b1e984e78bb8ca1bbbacf8b5e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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