Bromide ion → Ethyl (1RS)-1-(4-Fluorophenyl)-1-hydroxy-3-(3,4-methylenedioxyphenyl)indene-2-carboxylate

HRID 1563756Notes

Reaction equation

HRID 1563756 reaction equation
[Br-:25].[CH2:1]1[O:2][c:3]2[cH:4][c:5]([C:10]3=[C:11]([C:20](=[O:21])[O:22][CH2:23][CH3:24])[C:12](=[O:19])[c:13]4[cH:14][cH:15][cH:16][cH:17][c:18]43)[cH:6][cH:7][c:8]2[O:9]1.[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[F:26][c:27]1[cH:28][cH:29][c:30]([Mg+:33])[cH:31][cH:32]1>>[CH2:1]1[O:2][c:3]2[cH:4][c:5]([C:10]3=[C:11]([C:20](=[O:21])[O:22][CH2:23][CH3:24])[C:12]([OH:19])([c:30]4[cH:29][cH:28][c:27]([F:26])[cH:32][cH:31]4)[c:13]4[cH:14][cH:15][cH:16][cH:17][c:18]43)[cH:6][cH:7][c:8]2[O:9]1

Participants

5

Reactant 4

HCID 259Bromide ionHCID 8028TetrahydrofuranHCID 18427631Ethyl 3-(3,4-methylenedioxyphenyl)1-oxoindene-2-carboxylateHCID 178505839HCID 178505839, compound

Product 1

HCID 18969656Ethyl (1RS)-1-(4-Fluorophenyl)-1-hydroxy-3-(3,4-methylenedioxyphenyl)indene-2-carboxylate

Sources & evidence

ORD record
ord-75e1950eb5b24636bbcbc5a9b1ab6cd5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…