Trifluoroacetic acid → 3-(4-chlorobenzyl)-5-(3-fluoro-4-hydroxyphenyl)pyrimidin-4(3H)-one
Reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][n:7]2[cH:8][n:9][cH:10][c:11](-[c:14]3[cH:15][c:16]([F:28])[c:17]([O:20][CH2:21][c:22]4[cH:23][cH:24][cH:25][cH:26][cH:27]4)[cH:18][cH:19]3)[c:12]2=[O:13])[cH:29][cH:30]1.[OH:31][C:32]([C:33]([F:34])([F:35])[F:36])=[O:37]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][n:7]2[cH:8][n:9][cH:10][c:11](-[c:14]3[cH:15][c:16]([F:28])[c:17]([OH:20])[cH:18][cH:19]3)[c:12]2=[O:13])[cH:29][cH:30]1Participants
3
Sources & evidence
- ORD record
- ord-5ffc4dbd807e441d98b7c09f0dba6d58
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…