Potassium Cation → 1-(5-Isoquinolinylsulfonyl)piperazine

HRID 1564698Notes

Reaction equation

HRID 1564698 reaction equation
[C:7](=[O:8])([O-:9])[O-:10].[CH2:1]1[CH2:2][NH:3][CH2:4][CH2:5][NH:6]1.[CH2:27]([Cl:28])[Cl:29].[K+:11].[K+:12].[cH:13]1[n:14][cH:15][cH:16][c:17]2[c:18]([S:23](=[O:24])(=[O:25])[Cl:26])[cH:19][cH:20][cH:21][c:22]12>>[CH2:1]1[CH2:2][N:3]([S:23]([c:18]2[c:17]3[cH:16][cH:15][n:14][cH:13][c:22]3[cH:21][cH:20][cH:19]2)(=[O:24])=[O:25])[CH2:4][CH2:5][NH:6]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 4837PiperazineHCID 6344DichloromethaneHCID 19660Carbonate IonHCID 33716555-Isoquinolinesulfonyl chloride

Product 1

HCID 35451-(5-Isoquinolinylsulfonyl)piperazine

Sources & evidence

ORD record
ord-1767c5a924bd4da7aac3c1a2c82188ac
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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