Pyridine → 4-(4-Fluoro-2-(tetrahydro-2H-pyran-4-yloxy)phenylamino)-5-methylthieno[2,3-d]pyrimidine-6-carbonitrile
Reaction equation
[Cl:42][CH2:43][Cl:44].[F:1][c:2]1[cH:3][c:4]([O:22][CH:23]2[CH2:24][CH2:25][O:26][CH2:27][CH2:28]2)[c:5]([NH:8][c:9]2[c:10]3[c:11]([n:12][cH:13][n:14]2)[s:15][c:16]([C:19](=[O:20])[NH2:21])[c:17]3[CH3:18])[cH:6][cH:7]1.[F:29][C:30]([F:31])([F:32])[C:33]([O:34][C:35](=[O:36])[C:37]([F:38])([F:39])[F:40])=[O:41].[cH:45]1[cH:46][cH:47][n:48][cH:49][cH:50]1>>[F:1][c:2]1[cH:3][c:4]([O:22][CH:23]2[CH2:24][CH2:25][O:26][CH2:27][CH2:28]2)[c:5]([NH:8][c:9]2[c:10]3[c:11]([n:12][cH:13][n:14]2)[s:15][c:16]([C:19]#[N:21])[c:17]3[CH3:18])[cH:6][cH:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-f20567c8ba834c588f6703a2482706f4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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