Bromobenzene → 2-(3-Bromo-phenyl)-6-trifluoromethyl-4-(4-trifluoromethyl-phenyl)-pyridine

HRID 1565095Notes

Reaction equation

HRID 1565095 reaction equation
[BH:43]([OH:44])[OH:45].[Br:46][c:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1.[Cl:1][c:2]1[n:3][c:4]([C:18]([F:19])([F:20])[F:21])[cH:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([C:14]([F:15])([F:16])[F:17])[cH:12][cH:13]2)[cH:7]1.[I:22][c:23]1[cH:24][c:25](-[c:26]2[cH:27][cH:28][c:29]([C:30]([F:31])([F:32])[F:33])[cH:34][cH:35]2)[cH:36][c:37]([C:38]([F:39])([F:40])[F:41])[n:42]1>>[c:2]1(-[c:51]2[cH:50][cH:49][cH:48][c:47]([Br:46])[cH:52]2)[n:3][c:4]([C:18]([F:19])([F:20])[F:21])[cH:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([C:14]([F:15])([F:16])[F:17])[cH:12][cH:13]2)[cH:7]1

Participants

5

Reactant 4

HCID 7961BromobenzeneHCID 61668Boronic AcidHCID 574686352-Chloro-6-trifluoromethyl-4-(4-trifluoromethylphenyl)-pyridineHCID 574686722-Iodo-6-trifluoromethyl-4-(4-trifluoromethyl-phenyl)-pyridine

Product 1

HCID 574687952-(3-Bromo-phenyl)-6-trifluoromethyl-4-(4-trifluoromethyl-phenyl)-pyridine

Sources & evidence

ORD record
ord-a2aa9e847a5f4a9f8f3857181f6d8b53
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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