Methanol → 5-Bromo-2-hydroxy-6-(3-methylpiperidin-1-yl)-benzo[de]isoquinoline-1,3-dione
Reaction equation
[B+3:53].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][N:9]1[C:10](=[O:31])[c:11]2[cH:12][cH:13][cH:14][c:15]3[c:16]2[c:17]([cH:20][c:21]([Br:30])[c:22]3[N:23]2[CH2:24][CH:25]([CH3:29])[CH2:26][CH2:27][CH2:28]2)[C:18]1=[O:19].[CH3:54][OH:55].[F:32][C:33]([F:34])([F:35])[C:36]([O-:37])=[O:38].[F:39][C:40]([F:41])([F:42])[C:43]([O-:44])=[O:45].[F:46][C:47]([F:48])([F:49])[C:50]([O-:51])=[O:52].[F:57][C:58]([F:59])([F:60])[C:61]([OH:62])=[O:63].[OH2:56]>>[OH:8][N:9]1[C:10](=[O:31])[c:11]2[cH:12][cH:13][cH:14][c:15]3[c:16]2[c:17]([cH:20][c:21]([Br:30])[c:22]3[N:23]2[CH2:24][CH:25]([CH3:29])[CH2:26][CH2:27][CH2:28]2)[C:18]1=[O:19]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-d15745700b8f4b6baa3029b0a4a07585
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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