Dichloromethane → Piperidine-4-carboxylic acid (4-isopropyl-phenyl)-amide

HRID 1565384Notes

Reaction equation

HRID 1565384 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([C:14]([NH:15][c:16]2[cH:17][cH:18][c:19]([CH:22]([CH3:23])[CH3:24])[cH:20][cH:21]2)=[O:25])[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[CH2:33]([Cl:34])[Cl:35].[OH:26][C:27]([C:28]([F:29])([F:30])[F:31])=[O:32]>>[NH:8]1[CH2:9][CH2:10][CH:11]([C:14]([NH:15][c:16]2[cH:17][cH:18][c:19]([CH:22]([CH3:23])[CH3:24])[cH:20][cH:21]2)=[O:25])[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 292052294-(4-Isopropyl-phenylcarbamoyl)-piperidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 18071890Piperidine-4-carboxylic acid (4-isopropyl-phenyl)-amide

Sources & evidence

ORD record
ord-0956ef114bac4969a21023b1eba0a9f3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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