Sodium ion → 3-(6-(1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropane-carboxamido)-3-(hydroxymethyl)pyridin-2-yl)benzoic acid

HRID 1565438Notes

Reaction equation

HRID 1565438 reaction equation
[BH4-:1].[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[F:3][C:4]1([F:38])[O:5][c:6]2[c:7]([cH:9][cH:10][c:11]([C:13]3([C:16](=[O:17])[NH:18][c:19]4[cH:20][cH:21][c:22]([C:34](=[O:35])[O:36][CH3:37])[c:23](-[c:25]5[cH:26][c:27]([C:28](=[O:29])[OH:30])[cH:31][cH:32][cH:33]5)[n:24]4)[CH2:14][CH2:15]3)[cH:12]2)[O:8]1.[Na+:2]>>[F:3][C:4]1([F:38])[O:5][c:6]2[c:7]([cH:9][cH:10][c:11]([C:13]3([C:16](=[O:17])[NH:18][c:19]4[cH:20][cH:21][c:22]([CH2:34][OH:35])[c:23](-[c:25]5[cH:26][c:27]([C:28](=[O:29])[OH:30])[cH:31][cH:32][cH:33]5)[n:24]4)[CH2:14][CH2:15]3)[cH:12]2)[O:8]1

Participants

5

Reactant 4

HCID 923Sodium ionHCID 8028TetrahydrofuranHCID 28123BorohydrideHCID 591659443-(6-(1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-(methoxycarbonyl)pyridin-2-yl)benzoic acid

Product 1

HCID 591661043-(6-(1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropane-carboxamido)-3-(hydroxymethyl)pyridin-2-yl)benzoic acid

Sources & evidence

ORD record
ord-9eac97539de54708981d8ee3c6218480
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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