Dichloromethane → N-Methyl-N-(tetrahydro-2H-pyran-4-yl)-4-piperidinamine

HRID 1565662Notes

Reaction equation

HRID 1565662 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([N:14]([CH:15]2[CH2:16][CH2:17][O:18][CH2:19][CH2:20]2)[CH3:21])[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:29][CH2:30][Cl:31].[F:22][C:23]([F:24])([F:25])[C:26]([OH:27])=[O:28]>>[NH:8]1[CH2:9][CH2:10][CH:11]([N:14]([CH:15]2[CH2:16][CH2:17][O:18][CH2:19][CH2:20]2)[CH3:21])[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 59605945HCID 59605945, compound

Product 1

HCID 43611272N-Methyl-N-(tetrahydro-2H-pyran-4-yl)-4-piperidinamine

Sources & evidence

ORD record
ord-d1718558de2e4f7a9ad2fa65be3b62ee
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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