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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1565667Generated: November 2, 2026

Pyridine → 1-(4-Chloro-5-(1-ethyl-7-(1-methylpiperidin-4-ylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluorophenyl)-3-phenylurea

https://huagongshe.com/reaction/1565667

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridineHCID 1049—
ReactantDichloromethaneHCID 6344—
ReactantPhenyl isocyanateHCID 7672—
Reactant3-(5-amino-2-chloro-4-fluorophenyl)-1-ethyl-7-(1-methylpiperidin-4-ylamino)-1,6-naphthyridin-2(1H)-oneHCID 86713651—
Product1-(4-Chloro-5-(1-ethyl-7-(1-methylpiperidin-4-ylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluorophenyl)-3-phenylureaHCID 71585016—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-6e6514cdf2384b9694c97fe3dfb38f8e
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)