Dichloromethane → Ethyl 5-amino-1-(2-ethylphenyl)-6,8-difluoro-4-oxo-7-[2-(pyridin-2-ylamino)ethylamino]quinoline-2-carboxylate

HRID 1565758Notes

Reaction equation

HRID 1565758 reaction equation
[Cl:54][CH2:55][Cl:56].[F:1][c:2]1[c:3]([NH:37][CH2:38][c:39]2[cH:40][cH:41][c:42]([O:43][CH3:44])[cH:45][cH:46]2)[c:4]2[c:5](=[O:36])[cH:6][c:7]([C:31](=[O:32])[O:33][CH2:34][CH3:35])[n:8](-[c:23]3[c:24]([CH2:25][CH3:26])[cH:27][cH:28][cH:29][cH:30]3)[c:9]2[c:10]([F:22])[c:11]1[NH:12][CH2:13][CH2:14][NH:15][c:16]1[n:17][cH:18][cH:19][cH:20][cH:21]1.[OH:47][C:48]([C:49]([F:50])([F:51])[F:52])=[O:53]>>[F:1][c:2]1[c:3]([NH2:37])[c:4]2[c:5](=[O:36])[cH:6][c:7]([C:31](=[O:32])[O:33][CH2:34][CH3:35])[n:8](-[c:23]3[c:24]([CH2:25][CH3:26])[cH:27][cH:28][cH:29][cH:30]3)[c:9]2[c:10]([F:22])[c:11]1[NH:12][CH2:13][CH2:14][NH:15][c:16]1[n:17][cH:18][cH:19][cH:20][cH:21]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 66999800HCID 66999800, compound

Product 1

HCID 66999809Ethyl 5-amino-1-(2-ethylphenyl)-6,8-difluoro-4-oxo-7-[2-(pyridin-2-ylamino)ethylamino]quinoline-2-carboxylate

Sources & evidence

ORD record
ord-6b6446c4139a450280f878dc33ddbeab
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…