Triethylamine → rac-(2'S,3'S,4'S)-6-chloro-2'-(3-chloro-2-fluoro-phenyl)-4'-(2,2-dimethyl-propyl)-1'-[4-(3-methanesulfonyl-propyl)-piperazine-1-carbonyl]-1H-spiro[indole-3,3'-pyrrolidin]-2-one
Reaction equation
[CH3:32][S:33](=[O:34])(=[O:35])[CH2:36][CH2:37][CH2:38][N:39]1[CH2:40][CH2:41][NH:42][CH2:43][CH2:44]1.[CH3:45][CH2:46][N:47]([CH2:48][CH3:49])[CH2:50][CH3:51].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:9]([cH:10]1)[NH:8][C:7](=[O:11])[C:6]21[CH:12]([c:24]2[c:25]([F:31])[c:26]([Cl:30])[cH:27][cH:28][cH:29]2)[N:13]([C:21](=[O:22])[Cl:23])[CH2:14][CH:15]1[CH2:16][C:17]([CH3:18])([CH3:19])[CH3:20]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:9]([cH:10]1)[NH:8][C:7](=[O:11])[C:6]21[CH:12]([c:24]2[c:25]([F:31])[c:26]([Cl:30])[cH:27][cH:28][cH:29]2)[N:13]([C:21](=[O:22])[N:42]2[CH2:41][CH2:40][N:39]([CH2:38][CH2:37][CH2:36][S:33]([CH3:32])(=[O:34])=[O:35])[CH2:44][CH2:43]2)[CH2:14][CH:15]1[CH2:16][C:17]([CH3:18])([CH3:19])[CH3:20]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-7dd84ea953ac4f4b945bc7040d25eb2d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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