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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1566503Generated: November 3, 2026

N-(3-Iodo-4-methylphenyl)-4-((4methylpiperazin-1-yl) methyl)-3-(trifluoromethyl)benzamide → N-(3-[(8-aminoisoquinolin-4-yl)ethynyl]-4-methylphenyl}-4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)benzamide

https://huagongshe.com/reaction/1566503

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(3-Iodo-4-methylphenyl)-4-((4methylpiperazin-1-yl) methyl)-3-(trifluoromethyl)benzamideHCID 46838911—
Reactant4-Ethynylisoquinolin-8-amineHCID 86632312—
ProductN-(3-[(8-aminoisoquinolin-4-yl)ethynyl]-4-methylphenyl}-4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)benzamideHCID 24871564—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-6ffdc8afc1fc47ce8d5163e6cc4ca652
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)