Methane → tert-butyl N-methyl-N-(1-pyrrolidin-3-ylcyclopropyl)carbamate

HRID 156675Notes

Reaction equation

[C:31].[CH2:1]([O:2][C:3](=[O:4])[N:11]1[CH2:12][CH:13]([C:16]2([N:19]([CH3:20])[C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:17][CH2:18]2)[CH2:14][CH2:15]1)[c:5]1[cH:6][cH:7][cH:8][cH:9][cH:10]1.[CH3:28][CH2:29][OH:30].[Pd:32]>>[NH:11]1[CH2:12][CH:13]([C:16]2([N:19]([CH3:20])[C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:17][CH2:18]2)[CH2:14][CH2:15]1

Participants

Reactant 4

HCID 297Methane

HCID 702Ethanol

HCID 23938Palladium

HCID 22100494Benzyl 3-[1-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]cyclopropyl]pyrrolidine-1-carboxylate

Product 1

HCID 67271847tert-butyl N-methyl-N-(1-pyrrolidin-3-ylcyclopropyl)carbamate

Sources & evidence

ORD record: ord-50346b11486441d19d9407e17b2b17fd
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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