Potassium Cation → Tert-butyl 4-(2-(3,3-bis(4-fluorophenyl)-2-oxopyrrolidin-1-yl)ethyl)piperazine-1-carboxylate

HRID 1567115Notes

Reaction equation

HRID 1567115 reaction equation
[Br:27][CH2:28][CH2:29][N:30]1[CH2:31][CH2:32][N:33]([C:36](=[O:37])[O:38][C:39]([CH3:40])([CH3:41])[CH3:42])[CH2:34][CH2:35]1.[CH3:21][C:22]([CH3:23])([O-:24])[CH3:25].[F:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([c:14]3[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]3)[C:9](=[O:13])[NH:10][CH2:11][CH2:12]2)[cH:6][cH:7]1.[K+:26].[O:43]1[CH2:44][CH2:45][CH2:46][CH2:47]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([c:14]3[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]3)[C:9](=[O:13])[N:10]([CH2:28][CH2:29][N:30]3[CH2:31][CH2:32][N:33]([C:36](=[O:37])[O:38][C:39]([CH3:40])([CH3:41])[CH3:42])[CH2:34][CH2:35]3)[CH2:11][CH2:12]2)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 813Potassium CationHCID 8028TetrahydrofuranHCID 45749132-Methylpropan-2-olateHCID 15946441tert-Butyl 4-(2-bromoethyl)piperazine-1-carboxylateHCID 673585653,3-Bis(4-fluorophenyl)pyrrolidin-2-one

Product 1

HCID 67359885Tert-butyl 4-(2-(3,3-bis(4-fluorophenyl)-2-oxopyrrolidin-1-yl)ethyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-29674839bc7d458ea47ba546dba30248
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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