1,2-Dichloroethane → Methyl1-tert-butoxycarbonyl-4-fluoropyrrolidine-2-carboxylate

HRID 1567345Notes

Reaction equation

HRID 1567345 reaction equation
[CH2:18]([N:19]([S:20]([F:21])([F:22])[F:24])[CH2:23][CH3:25])[CH3:26].[Cl:32][CH2:33][CH2:34][Cl:35].[Na+:31].[O-:27][C:28]([OH:29])=[O:30].[OH:1][CH:2]1[CH2:3][CH:4]([C:14](=[O:15])[O:16][CH3:17])[N:5]([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:6]1>>[CH:2]1([F:24])[CH2:3][CH:4]([C:14](=[O:15])[O:16][CH3:17])[N:5]([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:6]1

Participants

6

Reactant 5

HCID 111,2-DichloroethaneHCID 769Bicarbonate IonHCID 923Sodium ionHCID 123472(Diethylamino)sulfur trifluorideHCID 51482991-Tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate

Product 1

HCID 11608471Methyl1-tert-butoxycarbonyl-4-fluoropyrrolidine-2-carboxylate

Sources & evidence

ORD record
ord-f2c33aac39b9434d97dd1315bc38eae9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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