Potassium Cation → 5-cyclopropyl-2-[4-(4-fluorophenoxy)phenyl]-N-methyl-6-[(methylsulfonyl)amino]-2H-indazole-3-carboxamide

HRID 1567530Notes

Reaction equation

HRID 1567530 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[n:9][c:10]3[cH:11][c:12]([NH:24][S:25](=[O:26])(=[O:27])[CH3:28])[c:13]([CH:21]4[CH2:22][CH2:23]4)[cH:14][c:15]3[c:16]2[C:17](=[O:18])[NH:19][CH3:20])[cH:6][cH:7]1.[C:29](=[O:30])([O-:31])[O-:32].[CH3:43][OH:44].[Cu:51][I:52].[Cu:53].[F:35][c:36]1[cH:37][cH:38][c:39]([OH:42])[cH:40][cH:41]1.[K+:33].[K+:34].[cH:45]1[cH:46][cH:47][n:48][cH:49][cH:50]1>>[c:2]1([O:42][c:39]2[cH:38][cH:37][c:36]([F:35])[cH:41][cH:40]2)[cH:3][cH:4][c:5](-[n:8]2[n:9][c:10]3[cH:11][c:12]([NH:24][S:25](=[O:26])(=[O:27])[CH3:28])[c:13]([CH:21]4[CH2:22][CH2:23]4)[cH:14][c:15]3[c:16]2[C:17](=[O:18])[NH:19][CH3:20])[cH:6][cH:7]1

Participants

9

Reactant 8

HCID 813Potassium Cation2×HCID 887MethanolHCID 1049PyridineHCID 97324-FluorophenolHCID 19660Carbonate IonHCID 23978CopperHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 56962687HCID 56962687, compound

Product 1

HCID 569626885-cyclopropyl-2-[4-(4-fluorophenoxy)phenyl]-N-methyl-6-[(methylsulfonyl)amino]-2H-indazole-3-carboxamide

Sources & evidence

ORD record
ord-47487afeed734078b96c4b0ab431d771
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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