Dichloromethane → 1-(4-bromo-2,5-difluoro-phenyl)-piperidin-4-one O-piperidin-4-yl-oxime

HRID 1567867Notes

Reaction equation

HRID 1567867 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][N:15]=[C:16]2[CH2:17][CH2:18][N:19]([c:22]3[c:23]([F:30])[cH:24][c:25]([Br:29])[c:26]([F:28])[cH:27]3)[CH2:20][CH2:21]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:38][CH2:39][Cl:40].[F:31][C:32]([F:33])([F:34])[C:35]([OH:36])=[O:37]>>[NH:8]1[CH2:9][CH2:10][CH:11]([O:14][N:15]=[C:16]2[CH2:17][CH2:18][N:19]([c:22]3[c:23]([F:30])[cH:24][c:25]([Br:29])[c:26]([F:28])[cH:27]3)[CH2:20][CH2:21]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 866550274-[1-(4-Bromo-2,5-difluoro-phenyl)-piperidin-4-ylideneaminooxy]-piperidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 866550281-(4-bromo-2,5-difluoro-phenyl)-piperidin-4-one O-piperidin-4-yl-oxime

Sources & evidence

ORD record
ord-7f233b8c3da64a12a6b5f48f9fec45dd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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