1-Methylimidazole → 4b-benzyl-7-hydroxy-N-(2-methyl-3-pyridinyl)-6-oxo-7-phenyl-8,8a,9,10-tetrahydro-5H-phenanthrene-2-carboxamide

HRID 1568739Notes

Reaction equation

HRID 1568739 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[C:8]12[c:9]3[cH:10][cH:11][c:12]([C:30](=[O:31])[OH:32])[cH:13][c:14]3[CH2:15][CH2:16][CH:17]1[CH2:18][C:19]([c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1)([OH:29])[C:20](=[O:22])[CH2:21]2.[CH2:47]([P:48]([OH:49])(=[O:50])[OH:51])[CH2:52][CH3:53].[CH3:41][n:42]1[cH:43][cH:44][n:45][cH:46]1.[CH3:54][C:55]#[N:56].[CH3:57][CH2:58][O:59][C:60](=[O:61])[CH3:62].[NH2:33][c:34]1[c:35]([CH3:40])[n:36][cH:37][cH:38][cH:39]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[C:8]12[c:9]3[cH:10][cH:11][c:12]([C:30](=[O:31])[NH:33][c:34]4[c:35]([CH3:40])[n:36][cH:37][cH:38][cH:39]4)[cH:13][c:14]3[CH2:15][CH2:16][CH:17]1[CH2:18][C:19]([c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1)([OH:29])[C:20](=[O:22])[CH2:21]2

Participants

7

Reactant 6

HCID 13901-MethylimidazoleHCID 6342AcetonitrileHCID 8857Ethyl AcetateHCID 204484Propylphosphonic acidHCID 5726163-Amino-2-methylpyridineHCID 178524090HCID 178524090, compound

Product 1

HCID 722417844b-benzyl-7-hydroxy-N-(2-methyl-3-pyridinyl)-6-oxo-7-phenyl-8,8a,9,10-tetrahydro-5H-phenanthrene-2-carboxamide

Sources & evidence

ORD record
ord-f4504b2fee54481f94421897eb7edcde
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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