Methanol → 4-(2-(4-Methyl-1H-pyrazol-1-yl)thieno[3,2-b]pyridin-7-yloxy)benzenamine

HRID 1568839Notes

Reaction equation

HRID 1568839 reaction equation
[CH2:28]1[O:29][CH2:30][CH2:31][CH2:32]1.[CH3:1][c:2]1[cH:3][n:4][n:5](-[c:7]2[cH:8][c:9]3[n:10][cH:11][cH:12][c:13]([O:16][c:17]4[cH:18][cH:19][c:20]([N+:23]([O-:24])=[O:25])[cH:21][cH:22]4)[c:14]3[s:15]2)[cH:6]1.[CH3:26][OH:27].[Ni:33]([Cl:34])[Cl:35]>>[CH3:1][c:2]1[cH:3][n:4][n:5](-[c:7]2[cH:8][c:9]3[n:10][cH:11][cH:12][c:13]([O:16][c:17]4[cH:18][cH:19][c:20]([NH2:23])[cH:21][cH:22]4)[c:14]3[s:15]2)[cH:6]1

Participants

5

Reactant 4

HCID 887MethanolHCID 8028TetrahydrofuranHCID 24385Nickel DichlorideHCID 594244922-(4-Methyl-1H-pyrazol-1-yl)-7-(4-nitrophenoxy)thieno[3,2-b]pyridine

Product 1

HCID 686921064-(2-(4-Methyl-1H-pyrazol-1-yl)thieno[3,2-b]pyridin-7-yloxy)benzenamine

Sources & evidence

ORD record
ord-cbb2ae1c393a49a6ab76334fd95aac12
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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