Water → 5,5,5-Trifluoro-4-hydroxy-2,2-bis[3-(trifluoromethoxy)phenyl]pentanenitrile
Reaction equation
[CH2:51]1[O:52][CH2:53][CH2:54][CH2:55]1.[CH3:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[CH3:8][CH2:9][CH2:10][CH2:11][Li:12].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[F:19][C:20]([O:21][c:22]1[cH:23][c:24]([CH:28]([C:29]#[N:30])[c:31]2[cH:32][c:33]([O:37][C:38]([F:39])([F:40])[F:41])[cH:34][cH:35][cH:36]2)[cH:25][cH:26][cH:27]1)([F:42])[F:43].[F:44][C:45]([CH:46]1[O:47][CH2:48]1)([F:49])[F:50].[OH2:56]>>[F:19][C:20]([O:21][c:22]1[cH:23][c:24]([C:28]([C:29]#[N:30])([c:31]2[cH:32][c:33]([O:37][C:38]([F:39])([F:40])[F:41])[cH:34][cH:35][cH:36]2)[CH2:48][CH:46]([C:45]([F:44])([F:49])[F:50])[OH:47])[cH:25][cH:26][cH:27]1)([F:42])[F:43]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-fd5237f935874610978434905ace2fc8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…