Formic Acid → 1,2,3,4-Tetrahydroisoquinoline

HRID 1569688Notes

Reaction equation

HRID 1569688 reaction equation
[CH2:36]1[NH:37][CH:38]=[CH:39][c:40]2[cH:41][cH:42][cH:43][cH:44][c:45]21.[CH3:29][CH2:30][N:31]([CH2:32][CH3:33])[CH2:34][CH3:35].[CH3:49][C:50]#[N:51].[CH:46]([OH:47])=[O:48].[NH2:1][CH:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[CH:9]([NH:10][S:11]([c:12]1[c:13]([CH3:14])[cH:15][c:16]([CH3:17])[cH:18][c:19]1[CH3:20])(=[O:21])=[O:22])[c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1>>[CH2:36]1[NH:37][CH2:38][CH2:39][c:40]2[cH:41][cH:42][cH:43][cH:44][c:45]21

Participants

6

Reactant 5

HCID 284Formic AcidHCID 6342AcetonitrileHCID 8471TriethylamineHCID 4225111,2-dihydroisoquinolineHCID 17822624HCID 17822624, compound

Product 1

HCID 70461,2,3,4-Tetrahydroisoquinoline

Sources & evidence

ORD record
ord-774e1dfb36534dc090efe6c612ea162d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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