Water → 2-(3-Chloro-2,4,5-trifluorophenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole
Reaction equation
[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[Cl:29][C:30]([Cl:31])([Cl:32])[C:33]([C:34]([Cl:35])([Cl:36])[Cl:37])=[O:38].[F:13][c:14]1[c:15]([C:22]2=[N:26][C:25]([CH3:27])([CH3:28])[CH2:24][O:23]2)[cH:16][c:17]([F:21])[c:18]([F:20])[cH:19]1.[OH2:44]>>[F:13][c:14]1[c:15]([C:22]2=[N:26][C:25]([CH3:27])([CH3:28])[CH2:24][O:23]2)[cH:16][c:17]([F:21])[c:18]([F:20])[c:19]1[Cl:29]Participants
7
Sources & evidence
- ORD record
- ord-ed48929da95b40a2b867176de225dff0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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