Water → Methyl 4-benzyloxycarbonyl-1-(3,4,5-trimethoxybenzoyl)-piperazine-2-carboxylate

HRID 1570212Notes

Reaction equation

HRID 1570212 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][CH:13]([C:17](=[O:18])[O:19][CH3:20])[NH:14][CH2:15][CH2:16]1.[CH3:21][CH2:22][N:23]([CH2:24][CH3:25])[CH2:26][CH3:27].[CH3:28][O:29][c:30]1[cH:31][c:32]([C:33](=[O:34])[Cl:35])[cH:36][c:37]([O:41][CH3:42])[c:38]1[O:39][CH3:40].[Cl:44][CH2:45][Cl:46].[OH2:43]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][CH:13]([C:17](=[O:18])[O:19][CH3:20])[N:14]([C:33]([c:32]2[cH:31][c:30]([O:29][CH3:28])[c:38]([O:39][CH3:40])[c:37]([O:41][CH3:42])[cH:36]2)=[O:34])[CH2:15][CH2:16]1

Participants

6

Reactant 5

HCID 962WaterHCID 6344DichloromethaneHCID 8471TriethylamineHCID 78282Benzoyl chloride, 3,4,5-trimethoxy-HCID 27573841-Benzyl 3-methyl piperazine-1,3-dicarboxylate

Product 1

HCID 54552702Methyl 4-benzyloxycarbonyl-1-(3,4,5-trimethoxybenzoyl)-piperazine-2-carboxylate

Sources & evidence

ORD record
ord-b11e596ff9b74e7ca3271a3ac77702d9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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