Dichloromethane → 2-[(3-chlorophenyl)-piperidin-3-ylmethoxy]-N-ethylacetamide

HRID 1570225Notes

Reaction equation

HRID 1570225 reaction equation
[Cl:36][CH2:37][Cl:38].[Cl:8][c:9]1[cH:10][c:11]([CH:15]([CH:16]2[CH2:17][N:18]([C:22]([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:28])[CH2:19][CH2:20][CH2:21]2)[O:29][CH2:30][C:31](=[O:32])[NH:33][CH2:34][CH3:35])[cH:12][cH:13][cH:14]1.[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7]>>[Cl:8][c:9]1[cH:10][c:11]([CH:15]([CH:16]2[CH2:17][NH:18][CH2:19][CH2:20][CH2:21]2)[O:29][CH2:30][C:31](=[O:32])[NH:33][CH2:34][CH3:35])[cH:12][cH:13][cH:14]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 68712098Tert-butyl 3-[(3-chlorophenyl)-[2-(ethylamino)-2-oxoethoxy]methyl]piperidine-1-carboxylate

Product 1

HCID 687136542-[(3-chlorophenyl)-piperidin-3-ylmethoxy]-N-ethylacetamide

Sources & evidence

ORD record
ord-e43af61fc0ad412fa85d278f79022836
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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