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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1570416Generated: November 4, 2026

Diethyl Ether → 5-Amino-1-(4-fluorophenyl)-N-{3,3,3-trifluoro-2-hydroxy-2-[(methylamino)methyl]propyl}-1H-pyrazole-4-carboxamide

https://huagongshe.com/reaction/1570416

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl EtherHCID 3283—
ReactantMethylamineHCID 6329—
ReactantTetrahydrofuranHCID 8028—
Reactant5-amino-1-(4-fluorophenyl)-N-{[2-(trifluoromethyl)-2-oxiranyl]methyl}-1H-pyrazole-4-carboxamideHCID 59487498—
Product5-Amino-1-(4-fluorophenyl)-N-{3,3,3-trifluoro-2-hydroxy-2-[(methylamino)methyl]propyl}-1H-pyrazole-4-carboxamideHCID 59487492—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-60ea68bc4c754bef9e771de4e844788c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)