Diethyl Ether → 5-Amino-1-(4-fluorophenyl)-N-{3,3,3-trifluoro-2-hydroxy-2-[(methylamino)methyl]propyl}-1H-pyrazole-4-carboxamide
Reaction equation
[CH3:25][NH2:26].[CH3:27][CH2:28][O:29][CH2:30][CH3:31].[NH2:1][c:2]1[c:3]([C:14](=[O:15])[NH:16][CH2:17][C:18]2([C:21]([F:22])([F:23])[F:24])[O:19][CH2:20]2)[cH:4][n:5][n:6]1-[c:7]1[cH:8][cH:9][c:10]([F:13])[cH:11][cH:12]1.[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1>>[NH2:1][c:2]1[c:3]([C:14](=[O:15])[NH:16][CH2:17][C:18]([OH:19])([CH2:20][NH:26][CH3:25])[C:21]([F:22])([F:23])[F:24])[cH:4][n:5][n:6]1-[c:7]1[cH:8][cH:9][c:10]([F:13])[cH:11][cH:12]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-60ea68bc4c754bef9e771de4e844788c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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