Tetrahydrofuran → N-[3-hydroxy-5-[[3-methyl-2-[[[methyl-[(2-propan-2-yl-4-thiazolyl)methyl]amino]-oxomethyl]amino]-1-oxobutyl]amino]-1,6-diphenylhexan-2-yl]carbamic acid 5-thiazolylmethyl ester
Reaction equation
[CH2:77]1[O:78][CH2:79][CH2:80][CH2:81]1.[CH3:41][N:42]([CH2:43][c:44]1[n:45][c:46]([CH:49]([CH3:50])[CH3:51])[s:47][cH:48]1)[C:52](=[O:53])[NH:54][CH:55]([CH:56]([CH3:57])[CH3:58])[C:59](=[O:60])[OH:61].[CH:62]1([N:63]=[C:64]=[N:65][CH:66]2[CH2:67][CH2:68][CH2:69][CH2:70][CH2:71]2)[CH2:72][CH2:73][CH2:74][CH2:75][CH2:76]1.[NH2:1][CH:2]([CH2:3][CH:4]([CH:5]([CH2:6][c:7]1[cH:8][cH:9][cH:10][cH:11][cH:12]1)[NH:13][C:14](=[O:15])[O:16][CH2:17][c:18]1[cH:19][n:20][cH:21][s:22]1)[OH:23])[CH2:24][c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1.[OH:31][n:32]1[c:33]2[c:34]([cH:35][cH:36][cH:37][cH:38]2)[n:39][n:40]1>>[NH:1]([CH:2]([CH2:3][CH:4]([CH:5]([CH2:6][c:7]1[cH:8][cH:9][cH:10][cH:11][cH:12]1)[NH:13][C:14](=[O:15])[O:16][CH2:17][c:18]1[cH:19][n:20][cH:21][s:22]1)[OH:23])[CH2:24][c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1)[C:59]([CH:55]([NH:54][C:52]([N:42]([CH3:41])[CH2:43][c:44]1[n:45][c:46]([CH:49]([CH3:50])[CH3:51])[s:47][cH:48]1)=[O:53])[CH:56]([CH3:57])[CH3:58])=[O:60]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-17b83e0580a241e2925839f42cf8b3ec
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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