N,N-Dimethylaniline → Ethyl 3-(4-Chloro-2,6-dimethylpyrimidin-5-yl)propionate

HRID 1570588Notes

Reaction equation

HRID 1570588 reaction equation
[CH3:1][c:2]1[n:3][c:4]([CH3:16])[c:5]([CH2:9][CH2:10][C:11](=[O:12])[O:13][CH2:14][CH3:15])[c:6](=[O:8])[nH:7]1.[CH3:22][N:23]([c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1)[CH3:30].[P:17]([Cl:18])([Cl:19])([Cl:20])=[O:21]>>[CH3:1][c:2]1[n:3][c:4]([CH3:16])[c:5]([CH2:9][CH2:10][C:11](=[O:12])[O:13][CH2:14][CH3:15])[c:6]([Cl:19])[n:7]1

Participants

4

Reactant 3

HCID 949N,N-DimethylanilineHCID 24813Phosphorus oxychlorideHCID 1359679873-(4-Hydroxy-2,6-dimethyl-pyrimidin-5-yl)-propionic acid ethyl ester

Product 1

HCID 14916837Ethyl 3-(4-Chloro-2,6-dimethylpyrimidin-5-yl)propionate

Sources & evidence

ORD record
ord-942f6913f8544c59a26234b3613eba90
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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